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Emergency crews are responding to a house fire in Creve Coeur Tuesday morning.

Police are investigating two separate deadly shootings involving two children. In the latest incident in Belleville, a 5-year-old girl was shot and killed.

Lottery players will have another shot Tuesday night at a massive Mega Millions prize that ranks as the third-largest jackpot in U.S. history. The estimated $1.55 billion prize has been gradually building for months thanks to 31 straight drawings without a jackpot winner. The last time someone won the game’s top prize was April 18. [...]

Anheuser-Busch InBev has reached an agreement to sell eight of its beer and beverage brands, including Shock Top and HiBall Energy, to a global cannabis company.

The state's health department is offering a chance for Missourians to become entrepreneurs in the marijuana industry. 

When we met Vanessa Downen in late July, the air conditioner in her Hazelwood Forest Apartment unit had been removed but not replaced.

Trash woes have now hit one of St. Louis's top suburbs. It's not an issue of too much garbage in Wildwood, it's too many garbage cans stacking up in people’s driveways, yards, or garages, along with skyrocketing garbage fees.

Two families are coping with tragedies. A 7-year-old was accidentally shot and killed in Berkeley. Hours later in Belleville, a 5-year-old suffered a fatal gunshot wound to the face.

Bands and music fans showed up to Ballpark Village Monday evening to celebrate the man lovingly known as Beatle Bob.

Baumgartner Road in south St. Louis County is badly in need of repair, and residents have long complained of the poor pavement and potholes.

An internal memo distributed to St. Louis police officers—and obtained by the FOX Files—reveals there were not enough dispatchers in the city this past Saturday evening.

The St. Louis County Police Department has cancelled an endangered person advisory from early Monday evening for a missing Florissant teenager.

More than 47,000 people in Illinois have lost their Medicaid coverage after a pandemic-era extension on their eligibility ended last week.

Republican lawmakers and anti-abortion activists are going back to court to fight a campaign to legalize abortion in Missouri. Abortion opponents on Monday filed a lawsuit against an initiative petition to enshrine abortion rights in the state constitution.

An Afghan man accused of sexually assaulting a 6-year-old boy last month appeared in St. Louis Circuit Court on Monday for a bond hearing.

It was another wild weekend of severe weather across the bi-state, with a few tornado touchdowns doing significant damage to rural communities. One community hit hard was Baring, Missouri, in Knox County.

SPRINGFIELD, Mo. - The Springfield Symphony Orchestra is joining forces once again with the St. Louis Ballet to bring Tchaikovsky’s "The Sleeping Beauty" to Springfield. The full-length ballet will close out the Symphony's 89th season on May 11, 2024. Tickets go on sale August 9, 2023, at Hammons Hall Box office. Group sales can be [...]

Tyson's report shows an income loss of $417 million, $1.07 per share, for July 2023. Just a year earlier had an income gain of $750 million, $2.07 per share.

ST. ANN -- A man is facing nine felony charges after a series of St. Louis County smoke shop burglaries that caused thousands of dollars in damages. The St. Louis County Prosecuting Attorney's Office says Cameron Tyler, 32, stole marijuana products and paraphernalia. After Tyler was arrested, police said that he admitted to the crimes. [...]

A 7-year-old was shot and killed Monday while allegedly playing with a loaded gun in a truck parked outside an apartment building.