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One person is dead after a two-car head-on crash in Cedar Hill.

One person is dead, and two juveniles are hurt after a series of shootings overnight in the city of St. Louis. Two others were also shot in the violence.

Social media posts about barking dogs have things getting out of hand in the Tower Grove South neighborhood. The posts have drawn an outlandish response—not on social media but on a 45-foot stretch of fencing along the yard where the dogs live.

One person is dead following a house fire Wednesday evening in St. Charles.

From running through crosswalks to speeding cars by kids walking and biking to school, parents are calling for an immediate change before someone is hurt.

United Auto Workers across the country could soon be going on strike. That means there could be a work stoppage at the General Motors Wentzville Assembly Center.

Senator Josh Hawley is going after credit card companies with new legislation aimed at the high interest rates they charge cardholders.

At the start of the school year, all you needed to get into a high school football game was a ticket, but that’s not the case anymore.

Richie Palacios homered, rookie Drew Rom and four relievers combined on a three-hitter and the St. Louis Cardinals beat Baltimore 1-0 Wednesday night to trim the Orioles' lead in the AL East to two games.

It’s a common decongestant ingredient found in hundreds of over-the-counter medications. But now, the FDA’s Nonprescription Drugs Advisory Committee says phenylephrine doesn’t actually get rid of nasal congestion.

A body was recovered from a lake at a south St. Louis park late Wednesday afternoon.

A University City family of 12 is homeless after a fire destroyed their house Tuesday.

Police in Troy, Illinois, are investigating a homicide involving a 60-year-old woman.

Missouri lawmakers have failed to override any of the governor's $555 million in budget cuts. The state Legislature convened Wednesday for its annual veto session.

A St. Louis man admitted to eight criminal charges, some in connection with the death of a De Smet Jesuit High School football coach in 2017.

A man has been sentenced to decades behind bars in connection with a violent encounter that led to shots fired last year in Hazelwood.

A Missouri judge has upheld the constitutionality of the state's Senate districts.

Missouri Attorney General Andrew Bailey filed a lawsuit Wednesday against Dollar General, claiming that hundreds of its retail stores in the state are offering "unfair and deceptive pricing."

UNIVERSITY CITY, Mo. -- A man is accused of breaking into several University City homes and threatening a homeowner with a knife. Kaleb Shillington is being charged with trespassing and unlawful use of a weapon. He is being held on a $50,000 cash-only bond. Officers were called to the 8100 block of Stanford at around [...]

Adam Wainwright only has a few more starts left in his illustrious career, and the St. Louis Cardinals have planned several days of celebrations for the grand finale.