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The 16th Gateway to Innovation Conference is Wednesday in St. Louis. More than 1,400 information technology workers will attend.

Clarksville officials are meeting Wednesday to begin planning for potential flooding.

Students from four local high schools are participating in a school safety forum Wednesday.

Iron County Sheriff Jeff Burkett is due in court Wednesday in Potosi.

A judge could decide whether to block the emergency rule on gender-affirming care filed by Missouri Attorney General Andrew Bailey Wednesday.

Several areas fire departments responded to a vacant house fire in Cahokia Heights.

One man is dead, and three others are hurt after the truck they are in is shot at, then crashes into a vacant home overnight in south St. Louis.

Multiple emergency crews were at the scene of a three-alarm fire at a University City pub and restaurant.

St. Louis Mayor Tishaura Jones delivered her second State of the City address on Tuesday.

St. Louis Mayor Tishaura Jones has made cleaning up St. Louis a priority, but in certain spots, the city's garbage crisis is worse than ever.

An investigation is underway after a man was found dead in a county jail hours after a car crash.

The mushroom hunter who found a woman's body in the woods Sunday night described the moments leading up to the tragic discovery.

In a case that 17 firefighters filed to get the city to pay them for what they earned, St. Louis Fire Chief Dennis Jenkerson gave testimony before a federal judge on Monday.

Fairmont City's Killian Weir was on his way to get groceries from East St. Louis's Save A Lot on Vieux Carre Drive when he noticed an empty parking lot and a sign on the supermarket's door.

A desperate tenant called FOX 2 for help after pipes in her government-subsidized apartment burst, flooding the upstairs and downstairs of the unit. Ceilings collapsed in at least two rooms, and the flooding has left an awful stench in her home on Thomas Street.

Congresswoman Cori Bush has introduced legislation calling for the cleanup of Jana Elementary and the testing of all schools in the Hazelwood School District for radioactive waste.

James O'Neal is charged in the fatal shooting of Phillip Smith in the former Norman Owens housing development in East St. Louis.

When St. Louis City SC goalkeeper and team captain Roman Burki had an incredible night against the Colorado Rapids, he was helping his team as well as some teenagers in the region.

The arrest of a pair of home burglary suspects in rural Illinois over the weekend led authorities to locate and apprehend a fugitive from Iowa.

A young man is dead after shots rang out Monday night in a Collinsville, Illinois, neighborhood. Multiple people are in custody, but police are still searching for one more suspect.