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Crews are at the scene of a tractor-trailer crash on Interstate 255 Wednesday morning.

SoutheastHEALTH, a health system based in Cape Girardeau, Missouri, has signed an agreement to become part of Chesterfield-based Mercy's health system, the organizations announced Tuesday.

Profanatica w/ Panzerfaust 7:30 p.m.

Ahead of last week’s Leagues Cup showdown with Club América, the group unveiled a tifo designed to unite St. Louis soccer fans.

34-year-old Osmani HaGee Goul's first court appearance has been rescheduled for Monday, August 7.

A man suspected of kidnapping his girlfriend's child in a stolen car is arrested Wednesday morning.  

One person was shot overnight at a 7-Eleven in Florissant.

A mess on Interstate 270 Wednesday morning after a crash involving three vehicles.

A man was struck by a car and killed overnight in north St Louis' Wells-Goodfellow neighborhood.

On the night of Saturday, June 22, Kelley Moulton knew instantly what the call she received from the chaplain at a local hospital meant. Her best friend was dying. 

Thousands of kids in the area will soon head back to school and St. Louis County officials want to make sure they have their vaccinations. That is why the St. Louis County Health Department is hosting multiple vaccination clinics.

We are tracking thunderstorms with heavy rainfall Wednesday morning. The heaviest rain is expected along and west of the Mississippi River.

Cottleville City Fields will cover 13 acres and feature two full-length soccer fields for youth club teams and individual training.

The state-of-the-art facility will initially house approximately 100 teams comprising 875 researchers, including experts in neurology, neuroscience, neurosurgery, psychiatry, and anesthesiology.

She worked with FDR and Eleanor Roosevelt, coordinated the now-famous Baby Tooth Survey, and helped make it easier for people to stay in their own homes as they age. Now, her sights are set on saving the planet and future generations.

If a director were filming a documentary about Gloria Gordon for her 100th birthday, they might start with her first job: organizing, at 22, a standing-room-only rally for presidential candidate Franklin Delano Roosevelt, which led to a second job that captured the interest of Eleanor Roosevelt. Or they might skip ahead to show Gordon in the 1960s, coordinating the now-famous Baby Tooth Survey, which gathered literal proof of radioactivity entering children’s bodies after above-ground tests of nuclear weapons.