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Emergency crews are at the scene of a fatal two-car crash Tuesday morning.

The Chesterfield-based health system signed a letter of intent to merge with another nonprofit health system that would expand its reach into southeast Missouri.

Southwest Airlines has hired former St. Louis-area Congressman Jerry Costello as a federal lobbyist, as it deals with fallout from its scheduling meltdown last month.

The deadly crash happened at 11:45 p.m. Monday on eastbound I-70, east of I-270.

Goldie Taylor faced many obstacles while growing up in East St. Louis and St. Ann, but followed a thirst for learning to a successful career as a writer. She describes the journey in her memoir, "The Love You Save."

One of St. Louis’ longest-running real estate and corporate relocation agencies has been acquired by one of the region’s largest real estate brokerages.

The Arts and Education Council of Greater St. Louis is leaderless — and quiet on the topic — as it moves to sell its long-time home, the Centene Center for the Arts in Grand Center. Lyah LeFlore-Ituen, who took the reins of the organization last July, said by phone on Friday that she is no longer with the Arts and Education Council. "I can confirm with you that I'm not the president and CEO," LeFlore-Ituen says.

Ballpark Village is hosting another job fair on Tuesday.

A new mural is going up at Anheuser-Busch to honor the world-famous Clydesdales' 90th anniversary this year.

Chances are you know about England’s Henry VIII and the fact that he had six wives. Henry’s matrimonial escapades were scandalous and, like the king himself, a bit larger than life.

The St. Louis Area Foodbank hosts a mobile food fair on Tuesday.

Mylissa Farmer said she was denied a life-saving abortion procedure at the Joplin hospital in August after her water broke early and put her health at risk.

New information has come out about a shooting that took place in a church cafeteria in East St. Louis on Sunday and killed one person.

The transition to sell both recreational and medical products also involves working with cities to change ordinances.

Monday alone, there were at least two separate $2,000 ticket buys, but one big spender took home $10,000 in tickets.

After stealing the car, police say two teens left the parking lot trying to escape but struck two cars just a few feet away and ran off.

Opening statements begin Tuesday, January 31 in the murder trial of Steven Johnson.

Police in Swansea, Illinois, are looking for a missing man Tuesday morning.

ST. LOUIS — Tuesday starts off in the teens with wind chills in the single digits to near zero. Some spots on the Illinois side of the river have wind chills below zero. Through the day, we'll have sunshine to…