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After expanding his Shake Shack brand in recent years, the restaurateur makes his mark in West Manhattan with an Italian-inspired concept.

After expanding his Shake Shack brand in recent years, the restaurateur makes his mark in West Manhattan with an Italian-inspired concept.

The company said its raise, plus two recent acquisitions, will help it to further develop ad verification, attribution and campaign coordination tools that help publishers monitor and understand the impact of advertisements.

The publicly traded biotechnology firm, which is developing treatments for infectious diseases, will open a new office and innovation lab within the Cortex innovation district. It already has ties to Washington University and Saint Louis University.

St. Louis County Executive Sam Page wants to put one of his predecessors, Charlie Dooley, on the 11-person Dome board that's set to get some part of the Rams lawsuit settlement.

Ringo Starr, Joe Walsh and Jeff Lynne are among the more than 40 celebrities featured in the first-ever official video for the late George Harrison's chart-topping 1970 hit "My Sweet…

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The victims in this case are all under the age of 5, police said.

The fundraiser begins at 4:30 a.m. Thursday and will last 24 hours.

Text the word TORNADO to 90999 to make a $10 donation to the Red Cross.

College football's early signing period starts today and runs through Friday. Here are the latest updates on where local stars are heading and how Mizzou and area colleges are doing.

Dr. Matifadza Hlatshwayo Davis doesn’t have the luxury to complain.

The policy begins Dec. 18, and comes months after other entertainment and sports venues already had the policy in place.

Dr. Alexander Garza of the St. Louis Metropolitan Pandemic Task Force said St. Louis is “losing ground” in the fight against COVID-19 during a briefing yesterday.

Joined by Dr. Clay Dunagan, Garza gave his first briefing since leaving to serve on a deployment to Kuwait as an Army physician. Now back in St. Louis, Garza said the number of hospitalizations due to COVID-19 is increasing, as well as the number of people in ICUs and on ventilators.…

On this edition of Politically Speaking, Senate Minority Leader John Rizzo speaks with STLPR's Jason Rosenbaum and Sarah Kellogg. Rizzo talked about his expectations for the 2022 session, how an election year brings more legislative obstacles as a result of political ambition, and the likelihood of Republicans drawing a 7-1 congressional redistricting map.

Photographer James Sapone, who went by Anthony, was fatally shot during an attempted carjacking on Cherokee Street on March 18, 2019.

Says monitoring of a summer breakfast and lunch program for lower-income children was ‘insufficient to ensure compliance’ with program requirements.

Elton John has notched a major milestone in his illustrious career: He's just scored his 70th entry on the Billboard Hot 100 chart. Sir Elton's holiday collaboration with Ed Sheeran,…

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Ask the experts from the Missouri Department of Transportation, St. Louis and St. Charles counties and St. Louis City your questions about highways and roads. The live chat starts at 1 p.m. on Wednesday.