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DONIPHAN, Mo. - The Doniphan Police Department has issued an Endangered Person Advisory Tuesday for a teen that may be on his way to the St. Louis area. According to police, 16-year-old Anthony James Guerra left his residence on Maple Street in the southern Missouri town of Doniphan Monday night around 11 p.m. A suicide [...]

Soprano Patricia Racette will become artistic director of the Opera Theatre of Saint Louis, filling a key management position of a company she has been associated with since her debut there in 1993. She will take over on Oct. 1 from James Robinson.

It's not just measles making a fierce comeback in 2025. Another disease that's especially dangerous to young children, known as pertussis or whooping cough, is spreading nearly twice as fast as it was last year.

A St. Louis woman faces a felony charge after she allegedly made dozens of 911 calls and threatened to "blow up" a police station, according to court documents obtained by FOX 2.

St. Louis County Prosecutor Melissa Price Smith will hold a news conference on Tuesday, May 6, to discuss her first 100 days in office and highlight key reforms, including reinstating the county's violent crime unit and reducing a significant backlog of cases by 43 percent.

ST. LOUIS - As our stubborn Ohio Valley low finally moves away, skies have cleared. Temperatures are cool Tuesday morning and there has been some fog developing. Expect those foggy areas to burn off quickly as the sun comes up. A sunny, warmer Tuesday for us, with high temperatures in the low to mid [...]

Every first Monday in May for nearly 50 years, Saint Louis University coaches, donors and players head to the Norwood Hills Country Club for an end-of-the-year celebration.

A trolley carrying dozens of people crashed Saturday morning near Hermann, Missouri, injuring 32 passengers, according to the Missouri State Highway Patrol.

Willson Contreras hit a go-ahead home run in a four-run sixth inning and the St. Louis Cardinals beat the Pittsburgh Pirates 6-3 on Monday night for their third straight victory.

An 11-year-old boy died from gunshot injuries in a shooting that happened in St. Louis tonight.

First Baptist Church in St. Ann is a mall congregation with a big problem.

Cinema St. Louis and the Hi-Pointe THeater announced that their $20,000 NEA grant for the 2025 St. Louis International Film Festival has been withdrawn.

Eight people were killed in a crash Sunday evening in Franklin County, Kansas.

The St. Louis Metropolitan Police Department (SLMPD) hosted its annual Memorial Breakfast today, honoring those lost in the line of duty. 

Businesses in Brentwood have their day in court against the City of Brentwood. Multiple businesses have sued the city to stop the city’s blight declaration of a stretch of Manchester Road.

With less than two weeks before graduation, seniors at the University of Missouri in Columbia are entering a job market that they say is tough.

A chop shop operator appeared in federal court Monday and admitted aiding car thieves connected to a St. Louis gang.

Those planning to travel by plane over the next several days will need to have their Real ID.

The Delmar Loop is celebrating Cinco De Mayo with its 3rd annual Taco Crawl, featuring eight restaurants with a wide range of unique taco options, and attendees can get their tickets for $35 to enjoy five tacos and redeem a free margarita at the Moonrise Hotel.

Homicide detectives are investigating a shooting that left one woman dead inside a home in the Dutchtown neighborhood on May 4.