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Police are still searching for the suspect in a shooting that's left a 16-year-old in critical condition. At the same time, a massive show of support for the teen and his family is growing by the minute.

A man was struck and killed along Interstate 270 early Tuesday evening, according to Florissant first responders.

With the return of cold temperatures and Thanksgiving gatherings comes the risk of the flu, colds, and this year—a rise in whooping cough cases.

There's a lot of foot traffic this time of year at St. Louis Lambert International Airport. The week of Thanksgiving is one of their busiest times of the year, with an estimated projection of 40,000 people traveling Tuesday and Wednesday. 

Cars were lined up for several blocks Tuesday to take advantage of the Urban League of Metropolitan St. Louis’ Annual Thanksgiving Turkey Giveaway.

The most wonderful time of the year can quickly turn tragic.

A man died Tuesday from injuries suffered in a wrong-way crash in St. Charles, police say.

A Hazelwood man has been charged with stealing $750 or more of power tools from a Menards near Manchester.

The Canadian Pacific Holiday Train, a festive cross-country holiday tradition on wheels, will roll through parts of Missouri and Illinois in the upcoming days.

JOLIET, Ill. — A Joliet man allegedly stole $45,000 worth of reindeer Christmas decorations from a baseball stadium. Victor Sessoms, 52, was arrested Monday afternoon in the 3900 block of Cedar Creek Drive on an arrest warrant for theft. He allegedly stole three Christmas reindeer decorations valued at a total of $45,000 from the loading [...]

A federal indictment accuses six people of installing skimming devices on St. Louis-area ATMs to obtain bank account information from customers.

A Venice, Illinois man appeared court on Monday and pleaded not guilty to a September carjacking in the city's Tower Grove East neighborhood.

Award-winning rapper and St. Louis native, Nelly, will host his annual star-studded Black and White Ball come December in support of the Make-A-Wish Missouri organization.

Wednesday morning marks the first time that temperatures officially dipped below the freezing point in St. Louis this fall. It's one of the latest dates for a first fall freeze in St. Louis since the National Weather Service began tracking such data.

Israel approved a United States-brokered ceasefire agreement with Lebanon's Hezbollah on Tuesday, setting the stage for an end to nearly 14 months of fighting linked to the ongoing war in the Gaza Strip.

Gioia's Deli, a beloved Italian sandwich eatery in the St. Louis region, is preparing to open a new restaurant next month in St. Charles County.

COLUMBIA, Mo. (AP) — A Missouri court on Monday upheld a new state law that bans some gender-affirming health care for minors, a victory for supporters of the ban as the Supreme Court prepares to hear a case on the issue next week. Republican Attorney General Andrew Bailey said in a statement that Missouri is [...]

A St. Louis County man has been charged with statutory sodomy for sexually abusing a 13-year-old, and police are seeking more potential victims.

For some people, their Thanksgiving is surrounded by home-cooked dishes in the comfort of their home. But for others, they may opt for restaurants to take care of the cooking and cleaning.

Police Chief Robert Tracy has provided updates on two high-profile cases in St. Louis, including a shooting on I-55 that injured a teen and the arrest of a suspect in the abduction and murder of Michelle Hampton, while also highlighting the department's efforts to combat crime and the low homicide rates.