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‘St. Louis needs the Cardinals to play baseball,’ said Ryan Loeffler, owner of Big Daddy’s bar in Soulard.

WASHINGTON — President Joe Biden’s first State of the Union address is set to focus significantly on the economy, with the former member of the U.S. Senate calling on Congress …

The mask mandates in St. Louis County and Illinois were lifted on Monday, while St. Louis city’s mask mandate remained in effect.

The Brian Laundrie autopsy included several answers about the final moments of his life, but the report prompted a big question for one retired FBI agent.

"Do I think that there is a reasonable chance of winning this this campaign? Yes, I do," Danforth said of his push for an independent Senate candidate.

The number of human trafficking cases in Missouri has nearly doubled in Missouri in the past five years, and advocates against trafficking are saying it's happening more often to kids because of the pandemic. 

Former St. Louis police officer Christopher Myers was expected to plead guilty Tuesday to a misdemeanor and face no jail time or fines for his role in the assault.

Well, good news for me, anyway. As many of you know, there's been an explosion in recent years of what are called CAR-T treatments for blood cancers in general and for multiple myeloma in particular. Unlike ordinary chemo treatments, CAR-T involves taking T cells from a patient (e.g., me) and shipping them off to a ...continue reading "Good news today!"

Raven Fox created the images supporting Ukraine after he read an email from a fellow artist, Val Syganevich, detailing the experiences of his staff in Kyiv.

The Affton food truck garden will offer Mardi Gras–themed cocktails, live music, and plenty of beads on March 1.

Police said a man lost his temper and punched his 3-month-old baby, severely injuring the child in O'Fallon, Missouri.

The longtime Fenton mayor said Monday he wanted to “ensure” the district would stay in Republican control.

Markquis Bryant pleaded guilty to a charge of distribution of a controlled substance related to an overdose death in 2020.

Election Board reverses previous decision and decides to list candidates for 28th Ward alderman in April 19 election as a Democrat and a Republican.

Dominic Wacker, 27, was charged with abuse or neglect of a child resulting in serious bodily injury. The child was hospitalized in critical condition.

St. Louis firms that have operations in Russia may be exposed to problems created by sanctions that are a response to the country's invasion of Ukraine, which began last week.