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Hospitals are caring for patients with less than half the blood supply typically on their storage shelves, St. Louis area surgeon says.

One person was injured when shots were fired inside the Fairview Heights mall on Thursday afternoon, police said.

Illinois Republicans say law targets Madison County, long a hub for lucrative asbestos litigation but whose voters have moved to the right.

Gov. Mike Parson believes a solution to the country’s supply chain issue is in the Show Me State. A group of logistics leaders met for the first time on Thursday.

A St. Louis man said he was reimbursed $9,000 for his grandmother's funeral costs. She died of COVID-19 after contracting the virus inside a nursing home.

A fire destroyed an apartment building Saturday morning in Cahokia Heights, Illinois. As many as 30 firefighters responded to the scene.

With abortion access increasingly restricted across much of the South and Midwest, two Illinois clinics near St. Louis announced Friday that they had set up a logistics center to help …